A novel genomic instability-derived lncRNA signature to predict prognosis and immune characteristics of pancreatic ductal adenocarcinoma

BackgroundPancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignant tumor of the digestive system.Its grim prognosis is mainly attributed to the lack of means for early diagnosis and poor response to treatments.Genomic instability is shown to be an important cancer feature and prognostic factor, and its pattern and extent may be asso

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Framework for treating non-Linear multi-term fractional differential equations with reasonable spectrum of two-point boundary conditions

In this work, a novel bio-inspired meta-heuristic framework is presented for the assessment of linear and non-linear multi-term fractional differential equations (MFDEs) based on the idea of residual power series method (RPSM) in amalgamation with the bat algorithm (BATA) which, mimics the echolocation behavior of the foraging lsu tote bag bats.The

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Can Sexual Selection Drive the Evolution of Sperm Cell Structure?

Sperm cells have undergone an extraordinarily divergent evolution among metazoan animals.Parker recognized that because female animals frequently mate with more than one male, sexual selection would continue after mating and impose strong selection on sperm cells to maximize fertilization success.Comparative analyses among species have revealed a g

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